The failure of malaria eradication in Ghana coupled with the prevailing environmental and economic conditions in the Ga East Municipality put majority of the inhabitants at high risk of malaria infection. This book presents the spatial prevalence of malaria and the coping strategies adopted to prevent and treat malaria in the Ga East Municipality. It was observed that the disease has consistently been the most predominant cause of morbidity and places a challenge on the health delivery system in the municipality. The book also shows that an interplay of environmental, economic and anthropogenic factors leads to differentials in vulnerability to malaria infections. Malaria also directly and indirectly affects the potential of an individual to undertake his or her daily economic activities, the ability to participate in community and religious gatherings. Malaria has the tendency of reducing household income and creates emotional and psychological distress. This book therefore identifies the weaknesses associated with the unavailability of basic services in urban fringes and how they affect health conditions. It is therefore recommended for experts who aim at solving health problems.